Pediatric Cancer Survivors


Pediatric Cancer Survivors carry a heavy risk for late morbidity and mortality, a consequence of the various therapeutic exposures that contribute to their cure. Focused surveillance for late therapy-related complications provides opportunities for early detection and implementation of health-preserving interventions. The substantial body of research that links therapeutic exposures used during treatment of pediatric cancer to adverse outcomes among survivors enables the characterization of groups at the simplest risk for developing complications related to specific therapies; however, methods available to optimize screening strategies to detect these therapy-related complications are limited. Moreover, the feasibility of conducting clinical trials to test screening recommendations for pediatric cancer survivors is proscribed by requirements for large sample sizes, lengthy study periods, prohibitive costs, and ethical concerns.



 


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