Rare tumours and Histiocytosis

A rare condition called Langerhans cell histiocytosis (LCH) starts in LCH cells. Dendritic cells of the LCH cell type are typically used by the body to fight infection. Genes that regulate the function of dendritic cells can occasionally undergo mutations (changes). Gene mutations in the BRAF, MAP2K1, RAS, and ARAF families are among them. In some areas of the body, these mutations may cause an excessive number of LCH cells to develop and accumulate, which could lead to lesions or tissue damage.

 

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