Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 24th World Congress on Pediatric Oncology and Cancer Care Frankfurt, Germany.

Day 1 :

  • Radiation Oncology, Colorectal Cancer and Stem cells, Cancer Causes and Diagnosis, Cancer Biomarkers, Cancer Therapeutics and Novel Approaches , Cancer management and preventions, Gynaecologic Oncology

Session Introduction

Nourhan Abdalkader

School of Pharmacy, Newgiza University, Cairo, Egypt

Title: Measuring the prevalence of fatigue in children with cancer: Evidence from Egypt.
Biography:

Abstract:

Background: Cancer related fatigue (CRF) is a common side effect of cancer and cancer treatment that impacts every aspect of quality of life. To our knowledge, the statistics for prevalence in pediatrics are lacking in Egypt. The aim of this study is to record the prevalence of fatigue and its significant predicting factors in pediatric oncology patients.

Methods:  we interviewed children aged 8-18 years with cancer, prescribed chemotherapy and not in severe distress. After the consent of the guardian is taken, the children personally filled 2 fatigue-related questionnaires (PROMIS Pediatric Short Forms of Fatigue (PROMIS fatigue), pedsQL multidimensional fatigue (PedsQL fatigue)) and 3 symptoms related questionnaires.

Results: 42 children (47.6% female) (mean age 12.1 years (SD 3.3 years)) participated. Half of the children were in primary school (n=21, 50%) and most of them had their parents accompanying them (n=35, 83.3%). Most children suffered from a hematological tumor (n=35, 83.3%) and didn’t suffer from other chronic health conditions (n=39, 92.8%). Reported moderate to severe fatigue in children is between half to third of the children depending on the measurement tool used. The mean T-score for PROMIS fatigue was 53.76 (SD 12.5), the mean score for PedsQL fatigue was 74.27 (SD 21.79). Stepwise standardized multivariant linear regression showed that fatigue following PROMIS fatigue could be predicted by depressive symptoms (𝜷= 0.47, p <0.001) and mobility (𝜷= -0.39, p =0.002) while following PedsQL fatigue, it could be predicted by upper extremity function (𝜷= 0.34, p= 0.005), depressive symptoms (𝜷=-0.49, p <0.001) and treatment status (𝜷=-0.25, p= 0.013).

Conclusion: CRF is multifactorial and prevalent among children and adolescents with cancer. Moreover, predicting factors differed between different tools as they measure fatigue from different dimensions. PedsQL fatigue was predicted by more factors. There is a need to include fatigue screening for pediatric oncology patients and incorporate its management in the medical care plan.

 

 

Biography:

Dr Vanessa Naguleswaran MBBS MRCPCH is a paediatric registrar ST5 trainee, with an interest in paediatric respiratory. Currently a Health Education England Education fellow, paediatric registrar representative and undertaking PGCert in Medical Education.

Abstract:

Background Suspicious neck lumps/lymphadenopathy is a very common reason for referral to paediatrics and for imaging via neck ultrasounds. Out of the paediatric urgent suspected cancer referrals, 39% are due to suspicious lymphadenopathy; however, literature states that isolated lymphadenopathy is a rare cause of malignancy. Aims • Aim to reduce the number of unnecessary neck ultrasound referrals to paediatric radiology and paediatric outpatient clinic for palpable lymph nodes in the neck • To create guidance when investigation or referrals are required for palpable lymph nodes in the paediatric population Method Collated a list of patients over a seven-month period retrospectively, of children that have had ultrasound neck requested by Basildon Radiology department. Then analyse the data to identify how many requests were rejected, cancelled, and authorised. Check how many reports were suggestive of malignancy. Results Out of 247 requests approximately 31% of Neck USS were cancelled/rejected/DNA. Out of a random sample of 50 patients, 0 patients were suspected malignancy. USS was not useful and did not change the management in 96% of the cases (apart from the one patient that had abscess and one patient who had suspected calculi). Recommendation • Present to ED, Paediatric doctors, GPs, Radiologists and Ultra sonographers. • To create a flowchart that can be disseminated to local GPs. • To check after implementation of the flow chart whether there has been a reduction in the number of unnecessary USS requests over a period.